Effective lipoprotein filtration with MONET®

MONET ® lipoprotein filtration

MONET® stands for Membrane Filtration Optimized Novel Extracorporeal Treatment.

Lipoprotein filtration with MONET® is used to reduce high molecular weight molecules such as:

  • High molcular weight lipoproteins — specifically LDL-C and Lp(a)
  • High molcular weight plasma proteins that are rheological relevant

The MONET® plasma fractionator contains a Fresenius Polysulfone® membrane, enhanced for use in lipoprotein filtration.

The membrane has the same excellent biocompatibilities as other Fresenius filters and is the result of our continuous product improvement procedures.

MONET® treatment procedure

During lipoprotein filtration, venovenous or AV fistula access can be used. The procedure consists of two steps: In step one, the plasma is separated from whole blood by plasma filtration or centrifugation. In step two, the plasma is passed through a second filter, the MONET® plasma fractionator. MONET® retains high-molecular components, such as:

  • Low density lipoprotein (LDL)
  • Very low density lipoprotein (VLDL)
  • Lp(a)
  • Triglycerides
  • Fibrinogen
  • IgM and IgA

Finally, the purified plasma is combined again with the whole blood and returned to the patient.

MONET plasma fractionation
MONET® runs as a plasma fractionator

Benefits of treatment with MONET®

Anticoagulation can be customized according to the patient’s needs

Clinical setup

MONET® can be carried out with:

  • Either the haemoadsorption machine Art Universal
  • Or a blood cell separator / centrifuge (e.g. COM.TEC®)
MONET clinical setup
MONET® clinical setup

Related therapies

1. Julius U et al.; Therapeutic Apheresis and Dialysis Apr. 2013; 17(2): 179–84.
2. Julius U et al.; Atherosclerosis Supplements May 2015; 18: 95–102