The new perspective on elevated Lp(a) levels
High levels of lipoprotein(a) [Lp(a)] also advance the development of atherosclerosis.
Lp(a) is structurally similar to LDL-C, with an additional apolipoprotein (apolipoprotein (a)) on the surface. The blood concentration is mainly genetically determined. The function and metabolism of Lp(a) are to date not fully understood.
However, there is a clear link between cardiovascular (CV) risk and Lp(a):
Lp(a) is a proven independent CV risk factor.2 Elevated Lp(a) levels cannot be efficiently managed through dietary measures or drug treatment.
Lipoprotein apheresis is the most effective method for removing Lp(a) in patients with Lp(a) levels of more than 60 mg/dL (120 mmol/L)3 and concomitant cardiovascular disease.
Above: Adapted from: “Harefield Hospital, Information about LDL apheresis”, © Royal Brompton & Harefield NHS Foundation Trust 2012.