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Prometheus® 4008H — dialysis and adsorption in one machine

Prometheus® 4008H therapy system

The Prometheus® 4008H therapy system fulfils two important therapeutic functions, dialysis and adsorption, in one machine.

The Prometheus® device is based on Fresenius Medical Care’s well-established dialysis system 4008H. Prometheus® combines an adsorptive process and high-flux hemodialysis.

In the first step, the patient's albumin (and the toxins bound to it) are separated from the blood by means of the special AlbuFlow® AF01 albumin filter. To remove the toxins, the albumin is passed over two adsorbers, prometh® 01 and prometh® 02. The adsorbers have a great affinity for the toxins and are therefore able to detach them from the albumin and bind them.

The purified albumin is then returned to the albumin filter and passed back to the blood. In the next step, water-soluble toxins are removed by hemodialysis.


Benefits of the Prometheus® system

Clinical setup

A clinical setup requires the Prometheus® 4008H device

Prometheus 4008H device
Prometheus® 4008H device

Related therapies

1. Krisper, Peter et al. Journal of Hepathology 2005; 43: 451–57.
2. Kribben, Andreas et al. Gastroenterology 2012; 142 (4): 782–89.